abstract：:Using extra- and intracellular recording techniques, we investigated the epileptiform activity induced by low concentrations (5 and 10 microM) of bath-applied 4-aminopyridine (4-AP) in the CA3 subfield of rat hippocampal slices. We also studied the effects of 4-AP on the excitatory and inhibitory synaptic conductance ...

journal_title：Journal of neurophysiology

authors： Rutecki PA,Lebeda FJ,Johnston D

更新日期：1987-06-01 00:00:00

abstract：:Single neurons were recorded from the ventral posteromedial thalamic nucleus (VPM) of urethan-anesthetized rats. Six of these animals were intact, 28 sustained kainic acid (KA) lesions of trigeminal nucleus principalis (PrV), and 9 received similar lesions of trigeminal subnucleus interpolaris (SpVi). Four animals sus...

journal_title：Journal of neurophysiology

authors： Rhoades RW,Belford GR,Killackey HP

更新日期：1987-05-01 00:00:00

abstract：:Intracellular recordings were performed in Cs-loaded sympathetic preganglionic neurons (SPNs) of the intermediolateral nucleus, identified by antidromic stimulation, in the slice of the T2 or T3 segment of the cat spinal cord. Loading the neurons with Cs resulted in broadening of the action potential, depression of th...

journal_title：Journal of neurophysiology

authors： Yoshimura M,Polosa C,Nishi S

更新日期：1987-05-01 00:00:00

abstract：:We have previously demonstrated that neurons R3-14 of the Aplysia abdominal ganglia specifically express a gene encoding a 108-amino acid neuropeptide precursor. This precursor is postranslationally processed by cleavage of a signal sequence and two internal dibasic residues resulting in three peptides. The peptide pr...

journal_title：Journal of neurophysiology

authors： Campanelli JT,Scheller RH

更新日期：1987-04-01 00:00:00

abstract：:Neurons in the visual cortex respond selectively to stimulus orientation and spatial frequency. Changes in response amplitudes of these neurons could be the neurophysiological basis of orientation and spatial frequency discrimination. We have estimated the minimum differences in stimulus orientation and spatial freque...

journal_title：Journal of neurophysiology

authors： Bradley A,Skottun BC,Ohzawa I,Sclar G,Freeman RD

更新日期：1987-03-01 00:00:00

abstract：:Fine flexible wire microelectrodes chronically implanted in the fifth lumbar ventral root (L5 VR) of 17 cats rendered stable records of the natural discharge patterns of 164 individual axons during locomotion on a treadmill. Fifty-one out of 164 axons were identified as motoneurons projecting to the anterior thigh mus...

journal_title：Journal of neurophysiology

authors： Hoffer JA,Loeb GE,Marks WB,O'Donovan MJ,Pratt CA,Sugano N

更新日期：1987-02-01 00:00:00

abstract：:We have used the rat hippocampal slice preparation as a model system for studying the epileptogenic consequences of a reduction in neuronal Na+-K+ pump activity. The cardiac glycosides (CGs) strophanthidin and dihydroouabain were used to inhibit the pump. These drugs had readily reversible effects, provided they were ...

journal_title：Journal of neurophysiology

authors： McCarren M,Alger BE

更新日期：1987-02-01 00:00:00

abstract：:Based on the findings of the preceding paper, it is known that auditory and visual signals have been translated into common coordinates at the level of the superior colliculus (SC) and share a motor circuit involved in the generation of saccadic eye movements. It is not known, however, whether the translation of senso...

journal_title：Journal of neurophysiology

authors： Jay MF,Sparks DL

更新日期：1987-01-01 00:00:00

abstract：:Ablation and single-unit studies in primates have shown that inferior temporal (IT) cortex is important for pattern discrimination. The first paper in this series suggested that single units in IT cortex of alert monkeys respond to a set of two-dimensional patterns with complex temporal modulation of their spike train...

journal_title：Journal of neurophysiology

authors： Optican LM,Richmond BJ

更新日期：1987-01-01 00:00:00

abstract：:Tetanus toxin reduces monosynaptic inhibitory and excitatory synaptic transmission in mouse spinal cord neurons in culture. Inhibitory transmission is preferentially reduced by the toxin; however, excitatory transmission is also ultimately reduced and blocked by the concentrations of toxin used in these studies. Recor...

journal_title：Journal of neurophysiology

authors： Bergey GK,Bigalke H,Nelson PG

更新日期：1987-01-01 00:00:00

abstract：:The ventroposterior region of the thalamus of mongrel cats was searched to locate zones activated by somatic stimuli. By using stimuli that selectively excited Pacinian corpuscles, areas activated by this class of afferent fibers were differentiated from regions activated by other classes of cutaneous mechanoreceptors...

journal_title：Journal of neurophysiology

authors： Herron P,Dykes R

更新日期：1986-12-01 00:00:00

abstract：:A total of 51 dorsal horn units responsive to heat were isolated and their receptive fields characterized (i.e., response properties and adequate stimuli determined) in pentobarbital-anesthetized, paralyzed rats. In 39 of the 51 units, the descending inhibition of heat-evoked activity produced by focal electrical stim...

journal_title：Journal of neurophysiology

authors： Jones SL,Gebhart GF

更新日期：1986-11-01 00:00:00

abstract：:The effect of stimulation of the laterodorsal tegmental nucleus (LDT) on the activity of single neurons in the dorsal lateral geniculate nucleus was studied in rats anesthetized with urethan. The LDT is the largest aggregation of cholinergic neurons in the brain stem that project to the thalamus, and in the rat is suf...

journal_title：Journal of neurophysiology

authors： Kayama Y,Takagi M,Ogawa T

更新日期：1986-11-01 00:00:00

abstract：:The characteristics of the primary afferent depolarization (PAD) of Ia- and Ib-fibers generated by segmental and descending inputs have been analyzed in the spinal cord of anesthetized cats. The PAD was inferred from the changes produced by conditioning inputs on the intraspinal stimulus current required to produce a ...

journal_title：Journal of neurophysiology

authors： Rudomin P,Solodkin M,Jiménez I

更新日期：1986-10-01 00:00:00

abstract：:Response properties of cells in the infragranular layers of cortical area 17 of the cat were examined in the absence of input from supragranular layers. Supragranular activity was silenced either reversibly by cooling the surface of cortex or permanently by making a cryogenic lesion of the supragranular layers. Visual...

journal_title：Journal of neurophysiology

authors： Schwark HD,Malpeli JG,Weyand TG,Lee C

更新日期：1986-10-01 00:00:00

abstract：:Single-unit electrical activity has been recorded from 122 viscerosomatic neurons in the T9 and T11 segments of the cat's spinal cord. These neurons were excited by electrical and/or natural stimulation of visceral and somatic afferent fibers. The majority of viscerosomatic neurons (72%) received somatic nociceptive i...

journal_title：Journal of neurophysiology

authors： Tattersall JE,Cervero F,Lumb BM

更新日期：1986-09-01 00:00:00

abstract：:The properties of the vestibuloocular reflex (VOR) when the axis of rotation is behind the eyes and fixation of a near target is required were studied in the monkey. The magnitude of VOR gain in each eye was found to be above 1.0 and near the ideal value for stabilizing a retinal image. Evidence that this large VOR ga...

journal_title：Journal of neurophysiology

authors： Viirre E,Tweed D,Milner K,Vilis T

更新日期：1986-08-01 00:00:00

abstract：:Responses have been recorded from primary endings of muscle spindles in the cat soleus muscle. Changes in spindle responsiveness were measured following a period of conditioning that consisted of a series of rapid stretches or of tetanic ventral root stimulation. In the testing procedure the response of a single spind...

journal_title：Journal of neurophysiology

authors： Gregory JE,Morgan DL,Proske U

更新日期：1986-08-01 00:00:00

abstract：:Conjugate eye movements in the horizontal plane are accomplished by the coactivation of the medial rectus (MR) muscle of one orbit and the lateral rectus (LR) muscle of the other. While control of these excursions has been thought to be effected by identical inputs to these muscles, recent studies have demonstrated th...

journal_title：Journal of neurophysiology

authors： Meredith MA,Goldberg SJ

更新日期：1986-07-01 00:00:00

abstract：:The lability of the responses of mammalian central neurons to gamma-aminobutyric acid (GABA) was studied using neurons acutely dissociated from the CA1 region of the adult guinea pig hippocampus as a model system. GABA was applied to the neuronal somata by pressure ejection and the resulting current (IGABA) recorded u...

journal_title：Journal of neurophysiology

authors： Huguenard JR,Alger BE

更新日期：1986-07-01 00:00:00

abstract：:Current and voltage-clamp recordings were made at room temperature from cultured mouse spinal neurons using conventional two-electrode voltage-clamp techniques and electrodes filled with either 3 M KCl, 3 M CsCl, or 3 M Cs2SO4. In the presence of tetraethylammonium and tetrodotoxin, "fast" (rapidly rising and falling)...

journal_title：Journal of neurophysiology

authors： Owen DG,Segal M,Barker JL

更新日期：1986-06-01 00:00:00

abstract：:The corticotectal influences of somatosensory cortex were investigated by using reversible deactivation of cortex by cooling. More than half of the somatosensory superior colliculus (SC) cells studied exhibited a response depression (often not apparent qualitatively) or an elimination of responses to somatosensory sti...

journal_title：Journal of neurophysiology

authors： Clemo HR,Stein BE

更新日期：1986-06-01 00:00:00

abstract：:Mechanisms of direction selectivity and speed selectivity were studied in single neurons of the middle temporal visual area (MT) of behaving macaque monkeys. Visual stimuli were presented in both smooth and stroboscopic motion within a neuron's receptive field as the monkey fixated a stationary point of light. Directi...

journal_title：Journal of neurophysiology

authors： Mikami A,Newsome WT,Wurtz RH

更新日期：1986-06-01 00:00:00

abstract：:The giant barnacle, Balanus nubilus, has three simple eyes, two lateral and one median. We have studied the convergence of the receptors of these ocelli by recording from the second-order cell (I-cell) and from the receptors' terminals. The I-cell's responses to illumination of the median and lateral eyes are similar ...

journal_title：Journal of neurophysiology

authors： Oland LA,Stuart AE

更新日期：1986-05-01 00:00:00

abstract：:A preparation is described in which the thoracic ganglia of the crayfish are isolated together with the thoracocoxal muscle receptor organ (TCMRO) of the fourth leg. This preparation allows intracellular analysis of both centrally generated and reflex activity in leg motor neurons (MNs). The isolated thoracic ganglia ...

journal_title：Journal of neurophysiology

authors： Sillar KT,Skorupski P

更新日期：1986-04-01 00:00:00

abstract：:The hearing ability of five Japanese macaques (Macaca fuscata) was assessed following two-stage bilateral auditory cortex lesions. The animals were tested using a shock-avoidance procedure with a conditioned-suppression procedure used for comparison in two cases. The animals initially were unable to respond to sound, ...

journal_title：Journal of neurophysiology

authors： Heffner HE,Heffner RS

更新日期：1986-02-01 00:00:00

abstract：:Intracellular recordings were made from rhythm-generating interneurons in the Lymnaea feeding system. The feeding pattern is a three-phase rhythm of interneuronal activity (N1, N2, N3) corresponding to protraction, rasp, and swallow. We describe the firing pattern and anatomy of the premotor interneurons, each of whic...

journal_title：Journal of neurophysiology

authors： Elliott CJ,Benjamin PR

更新日期：1985-12-01 00:00:00

abstract：:The pacemaker current of a bursting neuron of Helix pomatia was investigated using voltage-clamp and pressure-injection techniques. In the steady state the net membrane current was zero near threshold of the action potential at -45 mV. Negative to this potential the membrane current was inward and steady. During burst...

journal_title：Journal of neurophysiology

authors： Swandulla D,Lux HD

更新日期：1985-12-01 00:00:00

abstract：:Synaptic drugs were superfused into turtle eyecup preparation while recording extracellularly from directionally sensitive (DS) retinal ganglion cells. As in previous experiments in intact rabbit retina, both picrotoxin (a GABA antagonist) and physostigmine [an acetylcholine (ACh) potentiator] reduced or eliminated th...

journal_title：Journal of neurophysiology

authors： Ariel M,Adolph AR

更新日期：1985-11-01 00:00:00

abstract：:Electrophysiological properties of the ventral giant axon in the abdominal nerve cord of the cockroach were studied by recording intracellular potentials following partial or complete block of the K+ conductance. When the K+ conductance was completely blocked by tetraethylammonium (TEA) and 3,4-diaminopyridine, the in...

journal_title：Journal of neurophysiology

authors： Yawo H,Kojima H,Kuno M

更新日期：1985-11-01 00:00:00

abstract：:An acute experimental arthritis was induced in the right knee joint of adult cats anesthetized with chloralose, and the activity of single fine afferent units of the medial articular nerve was recorded from filaments of the saphenous nerve. All units included in this study were sensitive to local mechanical probing of...

journal_title：Journal of neurophysiology

authors： Schaible HG,Schmidt RF

更新日期：1985-11-01 00:00:00

abstract：:The activity patterns in self- and cross-reinnervated flexor digitorum longus (FDL) and soleus (SOL) muscles were examined during natural movements in awake, unrestrained cats in which electromyographic (EMG) electrodes, tendon-force gauges, and muscle-length gauges had been chronically implanted under anesthesia and ...

journal_title：Journal of neurophysiology

authors： O'Donovan MJ,Pinter MJ,Dum RP,Burke RE

更新日期：1985-10-01 00:00:00

abstract：:To investigate the dependence of velocity characteristics on spatiotemporal interactions the velocity selectivity of 15 geniculate and 72 cortical cells (areas 17 and 18) was examined with light and dark bars before and after masking all but the most sensitive part of the receptive field. The use of a 0.3 degree windo...

journal_title：Journal of neurophysiology

authors： Duysens J,Orban GA,Cremieux J

更新日期：1985-10-01 00:00:00

abstract：:Glass micropipettes were used to record the activity of 124 single units in the somatosensory vibrissa cortex (SI) of 16 rats in response to combined deflections of contralateral vibrissae. Compact multiangular electromechanical stimulators were used to stimulate individual vibrissal hairs alone or in combinations of ...

journal_title：Journal of neurophysiology

authors： Simons DJ

更新日期：1985-09-01 00:00:00

abstract：:Red and green cones of two turtle species (Pseudemys scripta elegans and Chelydra serpentina) retina have been stained with Golgi procedures and examined by light microscopy of whole-mount tissue and by electron microscopy of serial thin sections. By light microscopy, red and green single cones appear indistinguishabl...

journal_title：Journal of neurophysiology

authors： Kolb H,Jones J

更新日期：1985-08-01 00:00:00

abstract：:Mechanoreceptors of the crayfish tail fan have peripheral somata and send their axons to the last (sixth) abdominal ganglion via five bilateral pairs of nerve roots (R1-R5). Comparisons were made between normal crayfish and regenerate preparations in which R4 had been cut and directed back to an extensively denervated...

journal_title：Journal of neurophysiology

authors： Strandburg RJ,Krasne FB

更新日期：1985-08-01 00:00:00

abstract：:Single-unit activity was recorded from the caudate nucleus (CD), globus pallidus, and entopeduncular nucleus (GP-ENTO) in awake, partially restrained kittens. The purpose of this experiment was to assess the ability of developing basal ganglia structures to process natural facial somatosensory information and compare ...

journal_title：Journal of neurophysiology

authors： Schneider JS,Levine MS,Hull CD,Buchwald NA

更新日期：1985-07-01 00:00:00

abstract：:The scratch reflex is a motor task exhibited by the hindlimb of a turtle after complete transection of the spinal cord just posterior to the forelimb enlargement. The scratch is elicited by applying gentle tactile stimulation to a site innervated by spinal segments caudal to the level of the transection. During the sc...

journal_title：Journal of neurophysiology

authors： Mortin LI,Keifer J,Stein PS

更新日期：1985-06-01 00:00:00

abstract：:To estimate contour-orientation sensitivity of the cat and the degree to which precortical processing contributes to such estimates, the amplitude of visually evoked potentials (VEP) recorded from the visual cortex of cats in response to a visual stimulus (S2) presented at various intervals after presentation of anoth...

journal_title：Journal of neurophysiology

authors： Tootle JS,Berkley MA

更新日期：1985-05-01 00:00:00

abstract：:In this study we present further evidence supporting the reciprocal nature of output effects on forearm flexor and extensor muscles from single corticomotoneuronal (CM) cells. Spike-triggered averaging of rectified EMG activity was used to test the output effects of 105 motor cortex cells in two rhesus monkeys (Macaca...

journal_title：Journal of neurophysiology

authors： Kasser RJ,Cheney PD

更新日期：1985-04-01 00:00:00